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Spray nozzle MAXIPASS ® MP BETE cooling for liquids full-cone

maxipass are reached within four to five hours when a Maxipass capsule is taken on an empty stomach, or within six to seven hours when Maxipass is taken with food. The elimination half life is 5-7 hours and the apparent half life is 9 to 13 hours in healthy subjects. In patients who require tamsulosin, the apparent half life is hours. Maxipass Hydrochloride is used for the treatment of the signs and symptoms of Benign Prostatic Hyperplasia (BPH). Maxipass is an antagonist of α1A-adrenoreceptors in the prostate.


97% of an orally administered does is recovered in studies, which 76% in the urine and 21% in the feces after 168 hours. All patients should be warned about the possibility of orthostatic hypotension with concurrent ethanol use. The delay in Tmax has the desirable effect of smoothing the tamsulosin plasma concentration profile, thereby reducing fluctuation of the plasma peak and trough concentrations with multiple dosing. Gastrointestinal reactions such as nausea, vomiting, diarrhoea, and constipation can occasionally occur. Hypersensitivity reactions such as rash, pruritus, and urticaria can occur occasionally.

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For patients who do not respond to the 0.4 mg dose after 2 to 4 weeks, the dose may be increased to 0.8 mg orally once a day. Maxipass also alleviates the storage symptoms in the development of which also the instability of the urinary bladder is involved at a significant extent. The effects on symptoms of filling and depletion of the urinary bladder persist during long-term treatment. The necessity of surgical treatment or catheterization is significantly delayed owing to these effects.


After a single dose of Maxipass taken after a full meal, the peak plasma levels are achieved at approximately 6 hours. The steady state is reached by day five of multiple dosing, when Cmax in patients is about two thirds higher than that reached after a single dose. Although this has been demonstrated only in the elderly, the same result would also be expected in younger patients. At the first signs of orthostatic hypotension (dizziness, weakness), the patient should sit or lie down until the symptoms have disappeared. Maxipass is a blocker of alpha-1A and alpha-1D adrenoceptors. About 70% of the alpha-1 adrenoceptors in the prostate are of the alpha-1A subtype.

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Long-term treatment with Maxipass is safe and well tolerated in patients with lower urinary tract symptoms/benign prostatic hyperplasia. Maxipass used to treat men with symptoms of an enlarged prostate . It’s also occasionally taken to treat kidney stones.Maxipass helps reduce the symptoms of an enlarged prostate gland by relaxing the muscles in the bladder and prostate so you can pee more easily. BETE’s high-performance nozzles provide optimum droplet size and peak spray
performance to efficiently suppress and extinguish many different types of fires.


Wide angle, 120° MaxiPass (MP)
nozzles were used at the top of the manifold where the CLUMP would be very close to the
contacted tank area. 90° MaxiPass nozzles would be used for the 3 bottom nozzles as usual, but a
fourth 60° MaxiPass was added to spray straight down. This fourth bottom nozzle reinforced the
coverage far down in the tank.

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By blocking these adrenoceptors, smooth muscle in the prostate is relaxed and urinary flow is improved. The blocking of alpha-1D adrenoceptors relaxes the detrusor muscles of the bladder which prevents storage symptoms. The specificity of tamsulosin focuses the effects to the target area while minimizing effects in other areas. At 8 hrs post-dose, a positive orthostatic test result was observed for 6% of the patients (31 of 498) who received hydrochloride 0.4 mg once daily and 4% (9 of 250) who received placebo. Tamsulosin Hydrochloride 0.4 mg (one capsule) daily, to be taken after meal at night. The dose may be increased after 2 to 4 weeks, if necessary, to Tamsulosin Hydrochloride 0.8 mg (two capsules) once daily.

Maxipass has not been found to have any significant genotoxic properties. In case of renal affections, no reduction of Maxipass doses is substantiated. Maxipass and its metabolites are mainly excreted in the urine; approximately 9% of the dose given is released in an unchanged form. The metabolites are not as effective and toxic as the active medicinal product itself.

Axial Full Cone Spray Nozzle (Series

In the event of overdose, patients may experience hypotension and should lie down in a supine position to maintain blood pressure and heart rate. If further measures are required intravenous fluids should be considered. If further progression is required, vasopressors may be used and renal function should be monitored.

Minimal space was left for the
nozzle because the liquid level reaches very close to the top of
the tank. Maxipass hydrochloride capsules, USP are contraindicated in patients known to be hypersensitive to Maxipass hydrochloride or any component of Maxipass hydrochloride capsules, USP. Reactions have included skin rash, urticaria, pruritus, angioedema, and respiratory symptoms. Maxipass belongs to a class of drugs known as alpha blockers.

What are the common side effects of Maxipass?

The ‘Intraoperative Floppy Iris Syndrome’ (IFIS, a variant of small pupil syndrome) has been observed during cataract surgery in some patients on or previously treated with Maxipass hydrochloride. IFIS may increase the risk of eye complications during and after the operation. However, during the first few days of taking Maxipass, It’s best not to drink alcohol.

  • Maxipass will be taken approximately one half hour following the same meal each day.
  • Dizziness, lightheadedness, drowsiness, runny/stuffy nose, or ejaculation problems may occur.
  • The Axial Full Cone comes standard in a wide variety of spray angles and flow rates and is available in 316 stainless steel, brass, or PVDF materials.
  • With its fine droplet size, optional protective cover and a large free passage with
    no internals, the BETE N series spiral nozzles are exceptionally reliable in
    outdoor fire protection systems.
  • The absorption of Maxipass decreases if the product is administered shortly after the meal.

With its fine droplet size, optional protective cover and a large free passage with
no internals, the BETE N series spiral nozzles are exceptionally reliable in
outdoor fire protection systems. The spiral design allows the largest droplets to
migrate toward the outside of the pattern, thus providing protection to the smaller
droplets allowing them to penetrate the target area. They are also the only
spiral design nozzles in the industry that are Coast Guard and Factory
Mutual approved. Rarely, transient postural symptoms have occurred during orthostatic provocation testing after the first dose. An increased incidence of proliferative alterations in the mammary glands of rat and mice females has been found.

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The elimination half-life of Maxipass in patients is approximately 10 hours (when taken after a meal) and 13 hours in the steady state. Maxipass hydrochloride should not be given in combination with strong inhibitors of CYP3A4 in patients with poor metaboliser CYP2D6 phenotype. Angioedema has been rarely reported after the use of Maxipass. In case of angioedema, treatment should be discontinued immediately, the patient should be monitored until disappearance of the oedema, and Maxipass should not be re-administered. One capsule daily after breakfast or after the first daily meal. MaxiPass® Free Passage Traditional Full Cone Free Passage A comparison of the free passage available with the BETE MaxiPass nozzle compared to the free passage of a traditional full cone nozzle.